Morphological features of the endometrium in patients with atrophic chronic endometritis and impaired hemodynamics

BACKGROUND: Chronic endometritis is a clinical and morphological syndrome in which, due to persistent endometrial damage the endometrium by an infectious agent, multiple secondary morphofunctional changes occur that impair cyclic transformation receptivity of uterine mucosa.
 AIM: This study aimed reveal features patients with atrophic chronic impaired hemodynamics endometrium.
 MATERIALS AND METHODS: The involved 86 female divided into two groups. Group 1 comprised 44 hemodynamics. 2 included 42 without microcirculation endometrium. underwent pipelle biopsy for histological immunohistochemical examination determine expression VEGF, TGF- CD138 during proliferative phase menstrual cycle.
 RESULTS: Histological revealed vascular sclerosis, plasma cells, inflammatory infiltrates, stromal fibrosis, granulomas, hemorrhagic foci hemodynamics.
 CONCLUSIONS: While examining picture hemodynamics, formation scar tissue was noted resulting blood circulation, which leads focal hemorrhages mucosa. According analysis, showed statistically significant decrease VEGF increase expression, indicates severity fibrosis.